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Title: Eosinophilic granuloma. The management of solitary lesions of bone. Author: Greis PE, Hankin FM. Journal: Clin Orthop Relat Res; 1990 Aug; (257):204-11. PubMed ID: 2199118. Abstract: Solitary eosinophilic granuloma (EG) lesions of bone can represent diagnostic and treatment dilemmas for the orthopedic surgeon. A retrospective review of one institution's experience with isolated EG skeletal lesions over a 30-year period was undertaken. Solitary lesions responded well to most treatment modalities (e.g., curettage, excision, and irradiation) and infrequently resulted in functional impairment. While EG involvement in bone can be a manifestation of a systemic histiocytosis, single-focus skeletal involvement appears to be a benign pathophysiologic process.[Abstract] [Full Text] [Related] [New Search]