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  • Title: Reversible acute kidney injury (AKI) by active removal of serum light chains in an HIV positive patient with myeloma kidney.
    Author: Sowole L, Burns A, Kaur B, Davenport A.
    Journal: Clin Nephrol; 2011 Nov; 76(5):417-20. PubMed ID: 22000564.
    Abstract:
    BACKGROUND: The association of HIV and myeloma has rarely been reported in the literature. This following case discusses the presentation of acute kidney injury (AKI) in a 53-year-old lady with HIV, subsequently diagnosed with myeloma. Furthermore, we describe recovery of renal function and dialysis independence using a combination of light chain removal by dialysis with a high cut-off dialyzer and chemotherapy. INVESTIGATIONS: Physical examination, urine, blood tests, renal biopsy, bone marrow aspirate and trephine, US scan. DIAGNOSIS: Myeloma. MANAGEMENT: Dialysis and chemotherapy.
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