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  • Title: [Ultrasound echogenic splenic tumors: nodular manifestation of type C Niemann-Pick disease].
    Author: Fröhlich E, Harzer K, Heller T, Rühl U.
    Journal: Ultraschall Med; 1990 Jun; 11(3):119-22. PubMed ID: 2200110.
    Abstract:
    A female patient is described with highly echogenic splenic nodes found in routine diagnosis. After CT and angiography a splenectomy was carried out. The histological finding of sea blue histiocytes and the extended family history suggested a subtype of Niemann-Pick disease. Biochemical lipid analysis of the spleen confirmed Type-C Niemann-Pick disease. Niemann-Pick disease and its subtypes are discussed briefly.
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