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Title: Vessel connectivity using Murray's hypothesis. Author: Jiang Y, Zhuang ZW, Sinusas AJ, Staib LH, Papademetris X. Journal: Med Image Comput Comput Assist Interv; 2011; 14(Pt 3):528-36. PubMed ID: 22003740. Abstract: We describe a new method for vascular image analysis that incorporates a generic physiological principle to estimate vessel connectivity, which is a key issue in reconstructing complete vascular trees from image data. We follow Murray's hypothesis of the minimum work principle to formulate the problem as an optimization problem. This principle reflects a global property of any vascular network, in contrast to various local geometric properties adopted as constraints previously. We demonstrate the effectiveness of our method using a set of microCT mouse coronary images. It is shown that the performance of our method has a statistically significant improvement over the widely adopted minimum spanning tree methods that rely on local geometric constraints.[Abstract] [Full Text] [Related] [New Search]