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  • Title: [Hemolytic-uremic syndrome in an adult with T-cryptantigen liberation].
    Author: Rumpf KW, Lynen R, Verwiebe R, Schilling H, Neumeyer H.
    Journal: Dtsch Med Wochenschr; 1990 Aug 24; 115(34):1270-5. PubMed ID: 2202575.
    Abstract:
    Haemolytic uraemic syndrome was diagnosed in a 36-year-old woman with acute renal failure (creatinine 10.5 mg/dl), haemolytic anaemia (haemoglobin 9.7 g/dl, lactate dehydrogenase 1926 U/l) and thrombopenia (98,000/microliters). After initial plasmaphereses and high doses of furosemide all symptoms disappeared within three weeks. The lectin tests demonstrated that the illness was connected with the liberation of T-crypt-antigen (Thomsen-Friedenreich antigen) on the erythrocytes. This special form of the haemolytic uraemic syndrome (neuraminidase-induced haemolytic uraemic syndrome) has previously been observed almost exclusively in children. However, for diagnosis and differentiation of haemolytic uraemic syndromes the presence of liberated T-antigen on erythrocytes should also be tested for in adults.
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