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  • Title: [The changes of beta-glucuronidase in rabbit model with calcium bilirubinate stone].
    Author: Li N, Xiao L, Cheng S, Xiao B, Cheng W, Li Q.
    Journal: Hua Xi Yi Ke Da Xue Xue Bao; 1990 Jun; 21(2):185-7. PubMed ID: 2202652.
    Abstract:
    The aim of the present study is to determine the beta-glucuronidase changes in bile and hepatobiliary tissue of rabbit model having pigment gallstone by means of biochemical and enzymehistochemical assay methods. The result showed both of the bacterial and non-bacterial beta-glucuronidase take part in the course of pigment gallstone formation. The bacterial beta-glucuronidase level increased quickly before the formation of gallstone, then decreased with control of bacterial infection. Non-bacterial beta-glucuronidase increased slowly in pro-formation stage of gallstone, then kept high level for long period of time. The relationship between beta-glucuronidase and pigment gallstone formation is also discussed.
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