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  • Title: Dermatomyositis associated with generalized subcutaneous edema and Evans syndrome.
    Author: Jung KD, Kim PS, Park HY, Kim CR, Byun JY, Lee DY, Lee JH, Yang JM, Lee ES.
    Journal: J Am Acad Dermatol; 2012 Jan; 66(1):144-7. PubMed ID: 22030016.
    Abstract:
    Although periorbital edema is a common manifestation of dermatomyositis (DM), generalized subcutaneous edema associated with DM is extremely rare. Evans syndrome is an autoimmune disease in which an individual's antibodies attack one's own red blood cells and platelets. Evans syndrome is rarely a presenting feature of DM. DM has been rarely reported to be associated with either generalized edema or Evans syndrome. We report the case of a 52-year-old Korean woman who presented with generalized subcutaneous edema, an erythematous rash, dysphagia, and proximal muscle weakness, and subsequently developed features of Evans syndrome. Treatment with high-dose glucocorticoids and an immunosuppressive agent controlled the DM, the generalized subcutaneous edema, and the Evans syndrome.
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