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  • Title: [The basic features of the pathogenesis of pseudotuberculosis (yersiniosis)].
    Author: Avtsyn AP, Isachkova LM, Zhavoronkov AA, Somov GP, Makhnev MV.
    Journal: Arkh Patol; 1990; 52(5):3-7. PubMed ID: 2204325.
    Abstract:
    A new pathogenetic pattern of pseudotuberculosis has been derived on the basis of original clinical, anatomical and experimental findings as well as literature data. Careful consideration is given to: a basic mode of infection (alimentary), emergence of the primary affection with a rapid blood invasion by the agent (primary bacteremia), development of specific sensitization, multiorgan secondary focal impairment with lymphogenic dissemination of the infective agent (specific pseudotuberculous polyadenitis), formation of secondary immunodeficiency, consequent repeat bacteremias, recurrences, symptoms of infectious process aggravations, immunological rearrangement with dominating delayed hypersensitivity. As a rule, the disease terminated by elimination of the secondary foci and recovery.
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