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  • Title: Mass-to-splenic volume ratio and splenic weight as a percentage of body weight in dogs with malignant and benign splenic masses: 65 cases (2007-2008).
    Author: Mallinckrodt MJ, Gottfried SD.
    Journal: J Am Vet Med Assoc; 2011 Nov 15; 239(10):1325-7. PubMed ID: 22044329.
    Abstract:
    OBJECTIVE: To determine whether mass-to-splenic volume ratio or splenic weight as a percentage of body weight was significantly different between dogs with benign versus malignant splenic masses. DESIGN: Retrospective case series. ANIMALS: 65 dogs that underwent splenectomy. PROCEDURES: Medical records of dogs examined between October 2007 and June 2008 because of a splenic mass were reviewed. Information obtained included dog age, breed, and weight; whether hemoperitoneum was present; splenic weight and dimensions (length, width, and height) at the time of splenectomy; dimensions (length, width, and height) of the splenic mass; and histologic diagnosis. Information on survival time was recorded when available. RESULTS: 30 (46%) dogs had hemangiosarcoma, 10 (15%) had other types of malignant masses, and 25 (39%) had benign masses. Dogs with benign splenic masses had a significantly higher mean mass-to-splenic volume ratio and higher mean splenic weight as a percentage of body weight than did dogs with hemangiosarcoma. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that mass-to-splenic volume ratio and splenic weight as a percentage of body weight may be useful in differentiating between hemangiosarcoma and benign lesions in dogs with splenic masses.
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