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  • Title: [Titration and stability tests for antimeasles vaccine].
    Author: Ayala-González M.
    Journal: Bol Med Hosp Infant Mex; 1990 Jul; 47(7):512-5. PubMed ID: 2206418.
    Abstract:
    Production and quality of the vaccines, are important activities in the prevention of measles disease. Edmonston-Zagreb measles vaccine is the main strain attenuated virus distributed in México. In order to evaluate the titer of Edmonston-Zagreb and Schwarz vaccines, 50% tissue culture infective dose (TCID50/0.5 mL) and plaque-forming units (PFU) are performed in the National Laboratory of Public Health. Furthermore PFU is a method used in the stability vaccine test. Validation criteria are described in this paper.
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