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  • Title: Keratosis lichenoides chronica--case report.
    Author: Martins LC, Horne M, Moreira Júnior DN, Follador I, Almeida VR.
    Journal: An Bras Dermatol; 2011; 86(4 Suppl 1):S148-51. PubMed ID: 22068797.
    Abstract:
    Keratosis lichenoides chronica or Nekam's disease is a rare mucocutaneous dermatosis characterized by keratinization. It is chronic and progressive usually affecting individuals aged 20-40 years. Around 70 cases have been reported in the literature. Due to the rarity of this condition and the lack of effective treatment, it is a difficult disease to manage. In the case described below we present a 42-year old patient with violaceous and hyperkeratotic papules in linear, reticular or plaque form, located on the trunk and limbs for five years. Aphthous lesions in the oral cavity and shallow ulcers on the genitalia also formed part of the clinical manifestation. Pathologic examination was suggestive of keratosis lichenoides chronica. Acitretin and dapsone was introduced and the lesions partially improved.
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