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  • Title: Preparation of encapsulated alliinase in alginate microparticles.
    Author: Ko JA, Lee YL, Jeong HJ, Park HJ.
    Journal: Biotechnol Lett; 2012 Mar; 34(3):515-8. PubMed ID: 22072113.
    Abstract:
    Alliinase (alkylsulphenate lyase, EC 4.4.1.4), which catalyses the production of allicin, was immobilized in alginate microparticles. Addition of pyridoxal 5'-phosphate to the microparticles enhanced alliinase activity. Encapsulated alliinase were significantly higher (30 and 22%, respectively) than those of non-encapsulated alliinase at 60°C and at pH 2. Therefore, microencapsulation of alliinase with alginate can offer an effective way of sustaining enzyme activity during oral administration and passage through the stomach.
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