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  • Title: Synthesis of a new chemically stable prostacyclin analogue with high and long-lasting activity.
    Author: Iseki K, Kanayama T, Hayasi Y, Shibasaki M.
    Journal: Chem Pharm Bull (Tokyo); 1990 Jun; 38(6):1769-71. PubMed ID: 2208396.
    Abstract:
    The chemically stable prostacyclin analogue (Z)-4,5-didehydroisocarbacyclin analogue (6) has been synthesized. Compound 6 given intravenously or orally is very potent in inhibiting platelet aggregation.
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