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  • Title: Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors.
    Author: Yin Z, He Q, Huang X, Zhang J, Wu S, Chen P, Lu G, Chen P, Zhang Q, Yan Q, Zhang H.
    Journal: Nanoscale; 2012 Jan 07; 4(1):293-7. PubMed ID: 22089471.
    Abstract:
    A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO(2) wafer using the Langmuir-Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as the conductive channel in a solution-gated field effect transistor (FET), which is then used for real-time detection of hybridization of single-stranded DNA (ssDNA) with high sensitivity (2.4 nM). Such a simple, but effective method for fabrication of rGO-based transistors shows great potential for mass-production of graphene-based electronic biosensors.
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