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  • Title: Induction of the Escherichia coli cysK gene by genetic and environmental factors.
    Author: Yamamoto K, Oshima T, Nonaka G, Ito H, Ishihama A.
    Journal: FEMS Microbiol Lett; 2011 Oct; 323(1):88-95. PubMed ID: 22092684.
    Abstract:
    Cysteine synthase A encoded by cysK catalyzes the synthesis of cysteine from O-acetylserine. Expression of cysK in Escherichia coli is under the control of CysB, a LysR family transcription factor. Herein we showed that the expression of cysK is regulated by several genetic and environmental factors in addition to CysB: two genetic factors, OmpR and CysE, and lithium. Based on the findings, we constructed the high-level expression system of cysK.
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