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  • Title: pH-Uncontrolled lactic acid fermentation with activated carbon as an adsorbent.
    Author: Gao MT, Shimamura T, Ishida N, Takahashi H.
    Journal: Enzyme Microb Technol; 2011 May 06; 48(6-7):526-30. PubMed ID: 22113026.
    Abstract:
    In this paper, we presented a novel process involving activated carbon (AC) as an adsorbent for lactic acid fermentation, separation and oligomerization. It was found that pH has a significant effect on the adsorption of lactic acid on AC. The use of AC for in situ removal of lactic acid successfully decreased the inhibitory effect of lactic acid, resulting in significant increases in both productivity and yield. Acetone was used to desorb lactic acid and it was confirmed that the acetone treatment did not decrease the optical purity of the lactic acid, i.e., the optical purity was as high as 99.5% after desorption. Due to the presence of little materials influencing lactic acid oligomerization, oligomers with an optical purity of above 96% and a weight-average molecular weight (M(w)) of 2400 were obtained in the oligomerization process.
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