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  • Title: Simaomicin (LL-D42067), a novel antibiotic from Actinomadura madurae. I. Taxonomy, fermentation and biological activity.
    Author: Maiese WM, Korshalla J, Goodman J, Torrey MJ, Kantor S, Labeda DP, Greenstein M.
    Journal: J Antibiot (Tokyo); 1990 Sep; 43(9):1059-63. PubMed ID: 2211367.
    Abstract:
    A new antibacterial antibiotic, designated simaomicin alpha (LL-D42067 alpha) was isolated from the fermentation broth of an actinomycete strain. Based on cultural, physiological, morphological and chemical characteristics, culture LL-D42067 was identified as a new subspecies of Actinomadura madurae. Simaomicin alpha demonstrated potent activity against Gram-positive bacteria and was active in vivo against a variety of Eimeria species causing coccidiosis in chickens.
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