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  • Title: Dynamics of cerebrospinal fluid flow in slit ventricle syndrome.
    Author: Eymann R, Schmitt M, Antes S, Shamdeen MG, Kiefer M.
    Journal: Acta Neurochir Suppl; 2012; 113():181-6. PubMed ID: 22116448.
    Abstract:
    INTRODUCTION: Although slit ventricle syndrome (SVS) is identified as a serious complication in shunt-treated hydrocephalus, cerebral spinal fluid (CSF) flow via external ventricular drainage (EVD) or shunts in SVS have not been studied up to now. MATERIAL AND METHODS: A new apparatus (LiquoGuard(®); Möller-Medical, Fulda, Germany) was used for EVD in a child with SVS. The LiquoGuard actively controls CSF drainage, based on intracranial pressure (ICP). RESULTS: To achieve well-tolerated clinical conditions, an ICP level of 4 mmHg was necessary; realizable by drainage rates between 0 and 35 mL/h. Drainage rate variations typically occurred with repetitive time intervals of 2 h causing a "saw tooth" shaped CSF flow pattern throughout 24 h. DISCUSSION: SVS seems to be characterized largely by quickly varying CSF drainage demands. Whether this is a general phenomenon or just true for this case has still to be studied and needs further clarification.
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