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  • Title: Coumarin incorporated triazoles: a new class of anticonvulsants.
    Author: Bhat MA, Al-Omar MA.
    Journal: Acta Pol Pharm; 2011; 68(6):889-95. PubMed ID: 22125954.
    Abstract:
    A series of coumarin incorporated 1,2,4- triazole compounds (1-14) were evaluated for their possible anticonvulsant and neurotoxic properties, log P values, pharmacophoric mapping and three dimensional structure analysis. Compound (6) with para-fluoro substitution showed significant anticonvulsant activity.
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