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  • Title: Potential for immunization against herpesvirus infections with plasma membrane vesicles.
    Author: Pearson GR, Scott RE.
    Journal: IARC Sci Publ (1971); 1978; (24 Pt 2):1019-25. PubMed ID: 221369.
    Abstract:
    Virus-free, membrane antigen (MA)-positive plasma membrane vesicles produced from herpesvirus saimiri-infected owl monkey cells were used as immunogens in cotton-top marmosets. Neutralizing antibodies as well as antibodies to MA and HVS-induced LA were induced following immunization of marmosets with these vesicles. Preliminary findings demonstrated that immunized marmosets were significantly less susceptible to tumour induction by HVS than control animals.
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