These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Atherosclerosis and glomerulosclerosis in WHHL rabbits and obese Zucker rats.
    Author: Shimamura T, Amorosa LF, Wilson AC, Lelkes L, Khachadurian AK.
    Journal: Jpn J Exp Med; 1990 Jun; 60(3):105-9. PubMed ID: 2214254.
    Abstract:
    The aorta and the kidney of 12 month old hyperlipidemic WHHL and obese Zucker rats, were examined morphologically. The WHHL developed severe and premature atherosclerosis but did not develop glomerulosclerosis. In contrast, the Zucker rats did not manifest atherosclerosis of the aorta, but developed glomerulosclerosis. These two animal models could be useful in understanding the roles of heterogeneous lipoprotein particles, genetic susceptibility, hemodynamic stress, and mesangial interactions with lipoproteins in the development of glomerulosclerosis.
    [Abstract] [Full Text] [Related] [New Search]