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  • Title: Robust antimicrobial compounds and polymers derived from natural resin acids.
    Author: Wang J, Chen YP, Yao K, Wilbon PA, Zhang W, Ren L, Zhou J, Nagarkatti M, Wang C, Chu F, He X, Decho AW, Tang C.
    Journal: Chem Commun (Camb); 2012 Jan 21; 48(6):916-8. PubMed ID: 22143352.
    Abstract:
    We report novel robust resin acid-derived antimicrobial agents that exhibit excellent antimicrobial activities against a broad spectrum of bacteria (6 Gram-positive and 7 Gram-negative) with selective lysis of microbial membranes over mammalian membranes. Our results indicate that hydrophobicity and unique structures of resin acids can be determining factors in dictating the antimicrobial activity.
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