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  • Title: Short- and long-term effects of azadirachtin A on development and egg production of Rhodnius prolixus.
    Author: Garcia ES, Feder D, Gomes JE, Rembold H.
    Journal: Mem Inst Oswaldo Cruz; 1990; 85(1):11-5. PubMed ID: 2215221.
    Abstract:
    Azadirachtin A was given through a blood meal to 4th-instar larvae and to adult females of Rhodnius prolixus. Development (ecdysis) and egg production were inhibited in a dose-dependent manner. Long-term experiments with subsequent four feedings on azadirachtin-free blood were performed with 4th-instar larvae and with adult females. Only in the low-dose azadirachtin larval groups (0.01 and 0.1 microgram/ml of blood), development was partially restored; after a single 1.0 microgram/ml treatment about 50% of the treated larvae were still alive 120 days later without any adult emergence. Similarly fed females had a dose-dependent lower survival and egg deposition rate. The results are discussed in relation to the mode of azadirachtin A action.
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