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  • Title: Effect of maternal height and weight on risk of preterm birth in singleton and twin births resulting from in vitro fertilization: a retrospective cohort study using the Society for Assisted Reproductive Technology Clinic Outcome Reporting System.
    Author: Dickey RP, Xiong X, Gee RE, Pridjian G.
    Journal: Fertil Steril; 2012 Feb; 97(2):349-54. PubMed ID: 22154767.
    Abstract:
    OBJECTIVE: To examine the effect of height, weight, and body mass index (BMI) on the risk of preterm birth of singleton and twin pregnancies conceived by vitro fertilization (IVF). DESIGN: Retrospective cohort study using 2006-2008 data from the Society for Reproductive Technology Clinic Outcome Reporting System (SART CORS). SETTING: SART-associated assisted reproductive technology programs. PATIENT(S): 56,556 singleton and 23,804 twin live births resulting from fresh nondonor IVF cycles. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Rates of very early preterm (VEPTB; <28 weeks), very preterm (VPTB; <32 weeks), and preterm birth (<37 weeks) births. RESULT(S): In both singleton and twin births, increased maternal height was associated with a decreased risk of preterm birth. Maternal overweight and obesity were associated with significantly increased risk of VEPTB and VPTB in twin pregnancies. For very obese women (BMI > 35 kg/m(2)) twins were associated with a threefold increased risk of VEPTB (6.1% vs. 2.0%) and a twofold increased risk of VPTB (11.5% vs. 5.9%) compared with women of normal weight (BMI 18.4-24.9 kg/m(2)). CONCLUSION(S): Obesity and short stature significantly increase the risk of VEPTB and VPTB in twins conceived by IVF.
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