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  • Title: Comparison of ocular comfort, vision, and SICS during silicone hydrogel contact lens daily wear.
    Author: Diec J, Evans VE, Tilia D, Naduvilath T, Holden BA, Lazon de la Jara P.
    Journal: Eye Contact Lens; 2012 Jan; 38(1):2-6. PubMed ID: 22169881.
    Abstract:
    OBJECTIVES: The aim of this study was to investigate the relationship between solution-induced corneal staining (SICS) and silicone hydrogel contact lens comfort and vision. METHODS: A retrospective analysis of a series of open-label studies were conducted with 24 groups of approximately 40 participants, each wearing 1 of 6 silicone hydrogel contact lenses with 1 of 4 lens care products bilaterally for 3 months of daily wear. The presence of SICS and subjective ocular ratings were collected at 2 weeks and at 1 and 3 months. RESULTS: A total of 1,051 participants were enrolled. The participants with SICS rated significantly less favorably than did the participants without SICS for comfort during the day (7.9±1.7 vs. 8.5±1.4, P=0.03), comfort at the end of the day (6.6±2.1 vs. 7.4±1.9, P=0.03), overall dryness (7.4±1.9 vs. 8.0±1.7, P=0.04), dryness at the end of the day (6.7±2.2 vs. 7.5±2.1, P=0.01), feelings of burning and stinging (8.5±2.0 vs. 8.9±1.8, P=0.02), and overall vision (8.2±1.6 vs. 8.7±1.3, P<0.001). CONCLUSIONS: The participants with SICS had lower subjective comfort and vision compared with those who did not experience SICS.
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