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  • Title: Diterpenoids including a novel dimeric conjugate from Salvia leriaefolia.
    Author: Choudhary MI, Hussain A, Ali Z, Adhikari A, Sattar SA, Ayatollahi SA, Al-Majid AM.
    Journal: Planta Med; 2012 Feb; 78(3):269-75. PubMed ID: 22174076.
    Abstract:
    Salvialeriafone (1), a novel diterpene-norditerpene conjugate, was isolated from Salvia leriaefolia. Additionally, two new abietane-type diterpenoids, salvialerial (2) and salvialerione (3), as well as four known compounds, sugiol (4), salvicanaric acid (5), dehydroroyleanone (6), and cariocal (7), were isolated and identified. Their structures were determined by spectroscopic data analyses. Known compounds were isolated from this plant for the first time. Compounds 1, 5, 6, and 7 exhibited IN VITRO antiproliferative activity against the human cervical cancer cell line (Hela), while 6 showed cytotoxicity against the human prostate cancer cell line (PC3).
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