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  • Title: Subdiffraction scattered light imaging of gold nanoparticles using structured illumination.
    Author: Chang BJ, Lin SH, Chou LJ, Chiang SY.
    Journal: Opt Lett; 2011 Dec 15; 36(24):4773-5. PubMed ID: 22179879.
    Abstract:
    A reflective light-scattering (RLS) microscope with structured illumination (SI) provides subdiffraction resolution and improves the image quality of gold nanoparticles in biological systems. The three-dimensional (3D)-structured pattern is rapidly and precisely controlled with a spatial light modulator and scrambled at the conjugate image plane to increase spatial incoherence. The reconstructed SI-RLS image of 100 nm gold nanoparticles reveals lateral and axial resolutions of approximately 117 and 428 nm. We present a high-resolution image of gold nanoparticles inside a HeLa cell, with improved contrast.
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