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  • Title: Acid-base and electrolyte status during early induced pregnancy toxaemia in goats.
    Author: González FH, Hernández F, Madrid J, Martínez-Subiela S, Cerón JJ, Tecles F.
    Journal: Vet J; 2012 Aug; 193(2):598-9. PubMed ID: 22192407.
    Abstract:
    Eleven Murciano-Granadina goats in late pregnancy were separated into two groups (1) control (n=6) and (2) fasting for 72 h to induce pregnancy toxaemia (n=5). Venous blood was taken daily to determine acid-base and electrolyte parameters. Significant decreases in blood pH, bicarbonate concentration and base excess, and a significant increase in anion gap were observed after 24h of fasting. These changes were significantly correlated with non-esterified fatty acid concentration. No significant changes were observed in pCO(2), and electrolyte or lactate concentrations. Clinical signs of pregnancy toxaemia in fasted goats appeared by 72h post-fasting. These signs and the changes in acid-base balance disappeared once feed was reintroduced. Blood pH, bicarbonate concentration, base excess and anion gap could be indicators of early pregnancy toxaemia in goats.
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