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  • Title: [Early congenital lymphedema of the lower extremities combined with pachyonychia].
    Author: Sukolin GI, Pasportnikova OA.
    Journal: Vestn Dermatol Venerol; 1990; (6):60-3. PubMed ID: 2220066.
    Abstract:
    A four-year-old girl with early congenital lymphedema of the lower limbs in combination with the nail plate involvement (pachyonychia) is described. Such a combination is not characteristic of early lymphedema, it is usually described in late edema of the lower limbs. The described case was a sporadic one in the family. It cannot be excluded that lymphedema development was induced by impaired embryogenesis of the lymph vessels resultant from sulphanilamides intake for severe bronchitis that proband's mother had suffered during pregnancy.
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