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  • Title: The effect of short-term testosterone treatment in boys with delayed puberty.
    Author: de Lange WE, Snoep MC, Doorenbos H.
    Journal: Acta Endocrinol (Copenh); 1979 May; 91(1):177-83. PubMed ID: 222098.
    Abstract:
    Eight boys with severely delayed puberty without pathological cause were treated for 6 months with testosterone. This resulted in acceleration of skeletal maturation and a marked increase in height and weight. No adverse effects were found on hypothalamic-pituitary and gonadal maturation. Basal LH, FSH and testosterone levels rose to nearly adult values at follow-up within a year and pituitary responsiveness to LH-RH increased markedly.
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