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  • Title: [Pseudohypoparathyroidism type I and vitamin D therapy].
    Author: Kovarik J, Weissel M, Neuwirth G, Krepler P, Willvonseder R.
    Journal: Acta Med Austriaca; 1978; 5(3):106-9. PubMed ID: 222102.
    Abstract:
    In pseudohypoparathyroidism type I pharmacologic dosis of vitamin-D can correct hypocalcemia. Several authors who had investigated vitamin-D-metabolism in these patients, found impaired renal conversion of 25-hydroxyvitamin-D to 1,25-dihydroxy-vitamin-D. Treatment of 2 patients with pseudohypoparathyroidism type I with vitamin-D-3 and 1 alpha-Hydroxycholecalciferol consecutively resulted in a nonuniform response with regard to the normalisation of serum-calcium. This led us to the conclusion that the disturbances of vitamin-D-metabolism in pseudohypoparathyroidism type I is heterogenous.
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