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  • Title: Diffuse cutaneous leishmaniasis acquired in Peru.
    Author: Franke ED, Lucas CM, Tovar AA, Kruger JH, De Rivera MV, Wignall FS.
    Journal: Am J Trop Med Hyg; 1990 Sep; 43(3):260-2. PubMed ID: 2221221.
    Abstract:
    A case of diffuse cutaneous leishmaniasis (DCL) acquired in Peru is described. The causative agent was Leishmania mexicana amazonensis as determined by isoenzyme analysis and species-specific monoclonal antibody binding characteristics. Histological examination of biopsy material showed a large number of intracellular and extracellular amastigotes and few lymphocytes. Treatment with meglumine antimoniate (Glucantime) administered iv at a dosage of 20 mg antimony/kg body weight/day for 60 days resulted in visible improvement of the lesions, but not in clinical or parasitological cure.
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