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  • Title: Childhood osteosarcoma of greater wing of sphenoid: case report and review of literature.
    Author: Meel R, Thulkar S, Sharma MC, Jagadesan P, Mohanti BK, Sharma SC, Bakhshi S.
    Journal: J Pediatr Hematol Oncol; 2012 Mar; 34(2):e59-62. PubMed ID: 22217488.
    Abstract:
    Primary osteosarcoma of skull base is extremely rare. We present a case of primary osteosarcoma arising in greater wing of sphenoid in a child. Our patient had an incomplete excision after which he received adjuvant chemotherapy and radiotherapy. There was good response to adjuvant chemoradiotherapy and the patient is disease free at a follow-up of 18 months. Treatment of skull base osteosarcomas is difficult, as complete excision is often not possible. To the best of our knowledge, this is the first case of sphenoid wing osteosarcoma in childhood to be reported in literature.
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