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  • Title: Value of three-dimensional hysterosalpingo-contrast sonography with SonoVue in the assessment of tubal patency.
    Author: Zhou L, Zhang X, Chen X, Liao L, Pan R, Zhou N, Di N.
    Journal: Ultrasound Obstet Gynecol; 2012 Jul; 40(1):93-8. PubMed ID: 22223543.
    Abstract:
    OBJECTIVE: To investigate the accuracy of transvaginal three-dimensional hysterosalpingo-contrast sonography using SonoVue (3D SonoVue-HyCoSy) in the assessment of Fallopian tubal patency. METHODS: We recruited 75 infertile patients undergoing 3D SonoVue-HyCoSy before standard diagnostic laparoscopy with chromotubation (lap and dye). Tubal patency was assessed by automated 3D coded contrast imaging (3D SonoVue-HyCoSy), and the findings were compared with the results of lap and dye. RESULTS: For detecting tubal patency among the 150 Fallopian tubes assessed, 3D SonoVue-HyCoSy had a sensitivity of 93.5%, specificity of 86.3%, positive and negative predictive values of 87.8% and 92.6%, respectively, and diagnostic accuracy of 90.0%. The test-positive rates of 3D SonoVue-HyCoSy vs lap and dye were not significantly different (82/150 vs 77/150, P > 0.05). CONCLUSION: 3D SonoVue-HyCoSy should be considered clinically valuable as a practical, non-invasive, primary investigatory tool for evaluating tubal patency.
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