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Title: Mechanisms of hemostimulating effects of granulocytic CSF and pantohematogen under conditions of cytostatic myelosuppression. Author: Miroshnichenko LA, Shdanov VV, Zyuz'kov GN, Simanina EV, Stavrova LA, Udut EV, Khrichkova TY, Minakova MY, Goldberg VE, Dygai AM. Journal: Bull Exp Biol Med; 2011 Apr; 150(6):702-6. PubMed ID: 22235422. Abstract: We compared hemostimulating activity of pantohematogen and granulocytic CSF under conditions of 5-fluorouracil-induced cytostatic myelosuppression. It was found that activation of hemopoiesis regeneration under the effect of the test preparations was accompanied by the development of hyperplasia of the granulocytic and monocytic hemopoietic bone marrow lineages and more rapid recovery of the count of pholymorphonuclear leukocytes and monocytes in the peripheral blood (more marked under the effect of pantohematogen) followed by neutrophilia and monocytosis.[Abstract] [Full Text] [Related] [New Search]