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Title: Site-specific incorporation of diamondoids on DNA using click chemistry. Author: Crumpton JB, Santos WL. Journal: Chem Commun (Camb); 2012 Feb 14; 48(14):2018-20. PubMed ID: 22237385. Abstract: A simple and robust solid phase synthetic method for the ligation of diamondoids on the phosphate backbone of DNA with "click" chemistry using [Cu(CH(3)CN)(4)]PF(6) without a stabilizing ligand is reported. It was found that as the size of dimondoid increased, a corresponding increase in melting temperature was observed.[Abstract] [Full Text] [Related] [New Search]