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  • Title: Hemostimulating effects of erythropoietin immobilized by the nanotechnology method of electron-beam synthesis.
    Author: Dygai AM, Zyuz'kov GN, Zhdanov VV, Artamonov AV, Bekarev AA, Madonov PG, Kinsht DN, Udut EV, Miroshnichenko LA, Khrichkova TY, Simanina EV, Stavrova LA, Chaikovskiy AV, Markova TS, Minakova MY.
    Journal: Bull Exp Biol Med; 2011 Jun; 151(2):243-6. PubMed ID: 22238760.
    Abstract:
    The hemostimulating effect of erythropoietin immobilized by the nanotechnology method of electron-beam synthesis was studied on the model of carboplatin-induced myelosuppression. Subcutaneous injection or oral administration of immobilized erythropoietin was followed by stimulation of erythropoiesis. The effect was most pronounced after parenteral treatment with this agent. The increase in proliferative activity and maturation of erythroid precursor cells serve as a factor determining acceleration of reparative processes in the hemopoietic tissue.
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