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  • Title: Copper and selenium status of healthy pregnant women in Enugu, southeastern Nigeria.
    Author: Nwagha UI, Ogbodo SO, Nwogu-Ikojo EE, Ibegbu DM, Ejezie FE, Nwagha TU, Dim CC.
    Journal: Niger J Clin Pract; 2011; 14(4):408-12. PubMed ID: 22248939.
    Abstract:
    BACKGROUND: Copper and selenium are important trace elements in man. They function as antioxidants and play roles in oxido-reductase reactions. Several imported multivitamin preparations are given to our women during pregnancy and lactation to correct possible deficiencies. OBJECTIVE: The aim of the study is to determine the serum level of these micronutrients (selenium and copper) in a cross section of pregnant women in Enugu, southeastern Nigeria. MATERIALS AND METHODS: A cross section of 130 healthy pregnant women at different trimesters of pregnancy and 30 non-pregnant controls were selected from two health facilities in Enugu, southeastern Nigeria. Serum from the samples collected was assayed for copper and selenium using atomic absorption spectrophotometer. RESULTS: The mean copper level increased (P = 0.018), while the selenium level decreased (P < 0.0001) as pregnancy advanced. CONCLUSION: High copper levels indicate that supplementation should not be undertaken during normal pregnancy. Dietary intake should be modified to ensure optimal selenium levels during pregnancy.
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