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  • Title: Phytotoxicity of lignanamides isolated from the seeds of Hyoscyamus niger.
    Author: Zhang WN, Luo JG, Kong LY.
    Journal: J Agric Food Chem; 2012 Feb 22; 60(7):1682-7. PubMed ID: 22280058.
    Abstract:
    Bioassay-guided fractionation of phytotoxic extracts prepared from the seeds of Hyoscyamus niger led to the isolation of three new lignanamides (1-3), along with six known lignanamides (4-9). The structures of the new compounds were determined by spectroscopic methods, including 1D and 2D nuclear magnetic resonance techniques, and high-resolution electrospray ionization mass spectrometry. The bioactivity analysis of the isolated compounds showed that compound 3 exhibited significant inhibition on the germination and radical elongation of Allium fistulosum at 10(-4) M concentration.
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