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Title: Cranial mediastinal liposarcoma in a horse. Author: Kondo H, Wickins SC, Conway JA, Mallicote MF, Sanchez LC, Agnew DW, Farina LL, Abbott JR. Journal: Vet Pathol; 2012 Nov; 49(6):1040-2. PubMed ID: 22287648. Abstract: A 23-year-old Anglo-Arabian mare was presented with tachypnea, dyspnea, and pitting edema of the ventral thoracic subcutis. On necropsy, a tan to red, friable, irregularly shaped mass (23 × 20 × 18 cm) occupied the cranial mediastinum. Histologically, the mass was classified as a liposarcoma and was composed of short interlacing bundles of spindle-shaped to irregularly rounded cells with discrete, variably sized, clear cytoplasmic vacuoles, which were stained with oil red O in frozen sections of formalin-fixed tissue.[Abstract] [Full Text] [Related] [New Search]