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  • Title: Production and characterization of Clostridium perfringens recombinant β toxoid.
    Author: Milach A, de los Santos JR, Turnes CG, Moreira AN, de Assis RA, Salvarani FM, Lobato FC, Conceição FR.
    Journal: Anaerobe; 2012 Jun; 18(3):363-5. PubMed ID: 22306065.
    Abstract:
    In this work, we produced and evaluated a vaccine based on a β toxoid of Clostridium perfringens type C produced in Escherichia coli (rBT). The non-toxic rBT was innocuous for mice and induced 14 IU mL(-1) of β antitoxin in rabbits, complying with the European Pharmacopeia and CFR9 - USDA guidelines.
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