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  • Title: Cytotoxic triterpenoid saponins from Ardisia gigantifolia.
    Author: Mu LH, Wei NY, Liu P.
    Journal: Planta Med; 2012 Apr; 78(6):617-21. PubMed ID: 22314414.
    Abstract:
    Three new triterpenoid saponins, 1- 3, together with two known saponins, 4 and 5, were isolated from the rhizome of Ardisia gigantifolia. Their structures were elucidated by 1D and 2D NMR spectroscopic studies. Saponins 1, 2, 4, and 5 exhibited significant cytotoxicity against four human cancer cell lines, namely, Hela human cervical carcinoma cells, EJ human bladder tumor cells, HepG-2 human hepatoma cells, and BCG human gastric carcinoma cells with IC (50) values in the range of 1.9-4.8 µM.
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