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  • Title: Comparing the administration of fentanyl 1 µg kg⁻¹ and fentanyl 0.5 µg kg⁻¹ in dilation and curettage procedures.
    Author: Küçük M, Uğur B, Oğurlu M.
    Journal: Gynecol Endocrinol; 2012 Sep; 28(9):736-9. PubMed ID: 22316334.
    Abstract:
    PURPOSE: This study was carried out to compare fentanyl 0.5 µg kg⁻¹ -propofol as opposed to fentanyl 1 µg kg⁻¹ -propofol in terms of providing adequate analgesia, and a comparable recovery profile in dilation and curettage (D&C) procedures. METHODS: Verbal Pain Scale (VPS) scores, modified Aldrete scores, and hemodynamic parameters were recorded during and after the surgical procedure. In addition, a record was also kept of adverse events, and patients and surgeons were questioned about their satisfaction with the anesthesia. RESULTS: No difference was found between the two groups in terms of hemodynamic parameters, the VPS scores, or patient and surgeon satisfaction. The fentanyl 0.5 µg group displayed significantly higher modified Aldrete scores at both 5- and 10-min postoperative. Adverse events in both groups were considerably few. The incidence of postoperative nausea and vomiting (PONV) in the fentanyl 0.5 µg group was lower eventhough it did not reach the statistically significance level. In addition, faster recovery times were recorded with the administration of fentanyl 0.5 µg kg⁻¹ . CONCLUSION: Fentanyl 0.5 µg kg⁻¹ appears to be as reliable as that of fentanyl 1 µg kg⁻¹ with faster recovery times when used in D&C procedures.
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