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  • Title: Glycine catalyzed convenient synthesis of 2-amino-4H-chromenes in aqueous medium under sonic condition.
    Author: Datta B, Pasha MA.
    Journal: Ultrason Sonochem; 2012 Jul; 19(4):725-8. PubMed ID: 22325141.
    Abstract:
    A one-pot three-component condensation of an aldehyde, malononitrile, and resorcinol has been achieved by ultrasound method. The reaction has been catalyzed by glycine in aqueous medium. This protocol afforded corresponding 2-amino-4H-chromenes in shorter reaction times, high yields and simple work-up procedures with the green aspects by avoiding toxic reagents.
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