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  • Title: [Schistosoma-induced granulomatous panniculitis. An unusual presentation of cutaneous schistosomiasis].
    Author: Diallo M, Niang SO, Faye PM, Ly F, Ba A, Diop A, Gaye AM, Diatta BA, Thiam I, Ndiaye M, Diop NG, Dieng MT, Kane A.
    Journal: Ann Dermatol Venereol; 2012 Feb; 139(2):132-6. PubMed ID: 22325753.
    Abstract:
    BACKGROUND: Cutaneous schistosomiasis is extremely rare, even in endemic regions. It usually leads to non-specific papulonodular lesions in the perigenital area. We report a case of cutaneous schistosomiasis presenting as panniculitis. CASE REPORT: An 8-year-old girl was admitted for a large multinodular, indurated plaque over the perineum that gradually spread over a year in a setting of hypereosinophilia. Ultrasonography showed thickening of the bladder and a significant bilateral ureteral hydronephrosis. Histological examination revealed numerous granulomas Schistosoma haematobium ova at their centre and within the hypodermis. Treatment with praziquantel 40 mg/kg resulted in regression of cutaneous lesions within 3 weeks. DISCUSSION: We report a case of Schistosoma-induced granulomatous panniculitis that is noteworthy in terms of its clinical appearance, perineal location, association with severe urinary involvement and rapid regression under treatment. The current extent of endemic schistosomiasis and its severity justify greater awareness of this unusual cutaneous presentation, which to our knowledge has never previously been reported.
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