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  • Title: [Why chlorthalidone, the thiazide antihypertensive of choice, is neglected?].
    Author: Rumboldt Z.
    Journal: Lijec Vjesn; 2011; 133(11-12):408-10. PubMed ID: 22329298.
    Abstract:
    Diuretics, particularly thiazides and thiazide-like drugs, are antihypertensives of first choice. A prominent role in this group is reserved to chlorthalidone because of several pharmacological (e.g. longer biological half-life) and clinical advantages (e.g. superior reduction in cardiovascular events). Nevertheless, favored is hydrochlorothiazide, especially in fixed drug combinations, revealing a poor policy.
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