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  • Title: Neaumycin: a new macrolide from Streptomyces sp. NEAU-x211.
    Author: Huang SX, Wang XJ, Yan Y, Wang JD, Zhang J, Liu CX, Xiang WS, Shen B.
    Journal: Org Lett; 2012 Mar 02; 14(5):1254-7. PubMed ID: 22332843.
    Abstract:
    Neaumycin, a new 30-membered macrolide featuring an internal diester bridge, a molecular architecture that is unprecedented among known macrolide natural products, was isolated from a soil actinomycete strain Streptomyces sp. NEAU-x211. The structure of neaumycin was elucidated on the basis of comprehensive mass and NMR spectroscopic interpretation, including the relative stereochemistry of four independent coupling systems.
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