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  • Title: Photodynamic therapy in the management of circumscribed choroidal hemangioma.
    Author: Elizalde J, Vasquez L, Iyo F, Abengoechea S.
    Journal: Can J Ophthalmol; 2012 Feb; 47(1):16-20. PubMed ID: 22333845.
    Abstract:
    OBJECTIVE: To evaluate the efficacy of photodynamic therapy (PDT) for symptomatic circumscribed choroidal hemangioma (CCH). DESIGN: A retrospective case series analysis through chart review of patients with CCH treated by means of PDT. PARTICIPANTS: Thirteen patients with circumscribed choroidal hemangioma. METHODS: Through retrospective charts review, the patients' demographics, clinical features, management, and follow-up data were obtained and analyzed. Outcome measures were change in visual acuity, required sessions, and adjunctive treatments. RESULTS: Median follow-up was 26 months. Seven patients (54%) underwent only 1 session, 5 patients (38%) 2 sessions, and 1 received 5 sessions and was finally treated with external beam radiotherapy (EBRT). Visual acuity improved by at least 1 line (1-5) in 11 patients and remained stable in 2. Exudative subretinal fluid was completely resolved in 92% of the cases at the last visit. No major local side effects were found. CONCLUSIONS: PDT of CCH can effectively induce tumor regression and resolution of exudative subretinal fluid, improving, or stabilizing vision.
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