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  • Title: [Investigate the impact of hepatitis B virus infection on sperm DNA integrity].
    Author: Chen JW, Cui Y, Zhang XX.
    Journal: Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi; 2011 Oct; 25(5):345-7. PubMed ID: 22338220.
    Abstract:
    OBJECTIVE: Investigated the impact of HBV infection on sperm DNA integrity and its applied significance. METHODS: 12 cases infertility male with HBV infection in patient group and 11 cases of normal male without HBV infection in the control group were by SCD and CASA. RESULTS: The DFI in the patient group was (23.4 +/- 10.2)%, while it was in the control group was (11.6 +/- 5.9)%. The difference of the DFI in these two groups was significantly, P < 0.01. The sperm concentration and forward motility (a + b) in the patient group were lower than that in the control group, P < 0.01. There were also significantly of the normal sperm and sperm activity between the two groups. CONCLUSION: HBV infection not only affected the conventional semen parameters, but also caused serious damage on sperm DNA.
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