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  • Title: Immunocytochemical evidence for anti-LHRH and anti-ACTH activity in the "F" antiserum.
    Author: Clayton CJ, Hoffman GE.
    Journal: Am J Anat; 1979 May; 155(1):139-45. PubMed ID: 223429.
    Abstract:
    An antiserum which has previously been thought to be specific for LHRH-like immunoreactive material was shown to contain two populations of antibodies, one demonstrating anti-LHRH activity and the other anti-ACTH(1-24) activity. In rat and mouse, ACTH(1-24)-like immunoreactive substance is present in perikarya within the basal hypothalamus and in fibers in arcuate, periventricular and dorsomedial nuclei. LHRH-like immunoreactivity is present in fibers within the median eminence and arcuate nucleus, in a few fibers running along the ventral border of the hypothalamus, and in a small number of cell bodies within the medial basal hypothalamus.
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